Low dose typical antipsychotics – a brief evaluation
نویسندگان
چکیده
منابع مشابه
CATIE and Typical Antipsychotics
Introduction Atypical antipsychotics have largely replaced typical antipsychotics in clinical practice due to their perceived superiority in efficacy and lower risk of neurological adverse effects, which is believed to result in improved compliance. In fact, many treatment algorithms recommend the use of atypical antipsychotics as the only first-line medication treatment option. However, the Cl...
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A recall has been issued by Ortho-McNeil-Janssen Pharmaceuticals for specific lots of 3-mg Risperdal (risperidone) tablets and 2-mg generic risperidone tablets because of an uncharacteristic musty odor thought to come from trace amounts of 2,4,6-tribromoanisole (TBA), the metabolite of a chemical fungicide used to treat wooden pallets on which the products are stored.1 McNeil Consumer Health ha...
متن کاملDose response and dose equivalence of antipsychotics.
We review evidence from randomized, placebo-controlled studies of patients with schizophrenia or schizoaffective disorder, which compared 2 or more doses of an antipsychotic to calculate the dose-response curve for each first-generation (typical) antipsychotic (FGA) or second-generation (atypical) antipsychotic (SGA) and as a group (based on dose equivalence). We identified the near-maximal eff...
متن کاملLow dose radiation and circulatory diseases: a brief narrative review
Exposure to high doses of ionizing radiation is associated with damage to the heart and coronary arteries. However, only recently have studies with high-quality individual dosimetry data allowed this risk to be estimated while adjusting for concomitant chemotherapy. An association between lower dose exposures and late-occurring circulatory disease has only recently been suspected in the Japanes...
متن کاملLow dose vs standard dose of antipsychotics for relapse prevention in schizophrenia: meta-analysis.
BACKGROUND It remains unknown as to whether the antipsychotic dose needed for the acute-phase treatment of schizophrenia is also necessary for relapse prevention. AIM To compare the efficacy between standard dose [(World Health Organization daily defined dose (DDD)] vs low dose (≥50% to <1 DDD) or very low dose (<50% DDD) for relapse prevention in schizophrenia. DATA SOURCE Double-blind, ra...
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ژورنال
عنوان ژورنال: Psychiatric Bulletin
سال: 2001
ISSN: 0955-6036,1472-1473
DOI: 10.1192/pb.25.5.194